Pathguide: the pathway resource list
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Full Record: DEPOD  
Short NameDEPOD
Full Namethe human DEPhOsphorylation Database
URLhttp://depod.bioss.uni-freiburg.de/
Last ObservedMay 15th, 2017
DescriptionDephosphorylation Database (DEPOD) is a manually curated database collecting human active phosphatases, their experimentally verified protein and non-protein substrates and dephosphorylation site information and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates. DEPOD aims to be a valuable resource for: studying human phosphatases and their substrate specificities and molecular mechanisms; phosphatase-targeted drug discovery and development; connecting phosphatases with kinases through their common substrates; and completing the human phosphorylation/dephosphorylation network.
Sample Data URLhttp://depod.bioss.uni-freiburg.de/showp.php?gene=PTPN1
Data SourcePrimary
AvailabilityFree to all users
PubMed ArticlesElucidating human phosphatase-substrate networks.
Li X, Wilmanns M, Thornton J, Kohn M.
Sci Signal. 2013 May 14;6(275):rs10.


The human DEPhOsphorylation database DEPOD: a 2015 update.
Duan G, Li X, Kohn M.
Nucleic Acids Res. 2015 Jan;43(Database issue):D531-5.

Types of DataProtein-Protein Interactions, Metabolic Pathways, Signaling Pathways
Types of Tools
Contents
Small Molecules: 89
Genes / Proteins: 305
Interactions / Reactions: 1,114
Pathways: 979
Last Content Update: February 18th, 2016
Major OrganismsHomo sapiens
Relative Popularity
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"Pathguide: the pathway resource list" is maintained by Gary Bader1.
The website was originally created by Michael Cary 2 and was significantly updated and redesigned by Vuk Pavlovic1.
Thanks to Emek Demir for the Pathguide name.

1. Bader Lab
2. Sander Group

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