| BindingDB | | The Binding Database | | https://www.bindingdb.org/bind/index.jsp | | March 11th, 2017 | | A public database containing kinetic and thermodynamic binding constants for protein-ligand interactions. The data is only from isothermal titration calorimetry and enzyme inhibition experimental methods, but may include data from other methods in the future. The database is rigorously designed and implemented using the latest database technology. The search interface is very advanced and even allows searching for small molecules that are similar to an input structure. While it does contain information about biomolecular interactions, the data specification is focused on binding constant information and experimental method description for two specific methods. | | | | Primary | | Free to all users | BindingDB: a web-accessible molecular recognition database.
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Chen X, Lin Y, Liu M, Gilson MK.
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The binding database: overview and user
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BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities.
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Nucleic Acids Res. 2007 Jan;35(Database issue):D198-201. Epub 2006 Dec 1.
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Connecting proteins with drug-like compounds: Open source drug discovery workflows with BindingDB and KNIME.
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Database (Oxford). 2015 Sep 16;2015. pii: bav087.
BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology.
Gilson MK, Liu T, Baitaluk M, Nicola G, Hwang L, Chong J.
Nucleic Acids Res. 2016 Jan 4;44(D1):D1045-53.
| | Protein-Compound Interactions | | | Small Molecules: | 612,427 | | Genes / Proteins: | 7,196 | | Interactions / Reactions: | 1,373,032 | | Last Content Update: | August 1st, 2017 |
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