Pathguide: the pathway resource list
Home BioPAX cBio MSKCC
Full Record: FlyBase  
Short NameFlyBase
Full NameFlyBase: a database of Drosophila Genes & Genomes
Last ObservedFebruary 8th, 2017
DescriptionFlyBase is a database revolving around drosophila melanogaster. The database provides descriptive information regarding drosophila melanogaster, such as genetic interactions, protein-protein interactions and interactive genomic maps. The data can be accessed through a simple keyword search or it can be downloaded.
Sample Data URL 
Data SourceSecondary
AvailabilityFree to all users
PubMed ArticlesFlyBase: genomes by the dozen.
Crosby MA, Goodman JL, Strelets VB, Zhang P, Gelbart WM; FlyBase Consortium.
Nucleic Acids Res. 2007 Jan;35(Database issue):D486-91.

FlyBase: integration and improvements to query tools.
Wilson RJ, Goodman JL, Strelets VB; FlyBase Consortium.
Nucleic Acids Res. 2008 Jan;36(Database issue):D588-93.

FlyBase : a database for the Drosophila research community.
Drysdale R; FlyBase Consortium.
Methods Mol Biol. 2008;420:45-59.

FlyBase: enhancing Drosophila Gene Ontology annotations.
Tweedie S, Ashburner M, Falls K, Leyland P, McQuilton P, Marygold S, Millburn G, Osumi-Sutherland D, Schroeder A, Seal R, Zhang H; FlyBase Consortium.
Nucleic Acids Res. 2009 Jan;37(Database issue):D555-9.

Inside FlyBase: biocuration as a career.
St Pierre S, McQuilton P.
Fly (Austin). 2009 Jan-Mar;3(1):112-4.

FlyBase 101--the basics of navigating FlyBase.
McQuilton P, St Pierre SE, Thurmond J; FlyBase Consortium.
Nucleic Acids Res. 2012 Jan;40(Database issue):D706-14.

FlyBase: improvements to the bibliography.
Marygold SJ, Leyland PC, Seal RL, Goodman JL, Thurmond J, Strelets VB, Wilson RJ; FlyBase consortium.
Nucleic Acids Res. 2013 Jan;41(Database issue):D751-7.

Opportunities for text mining in the FlyBase genetic literature curation workflow.
McQuilton P; FlyBase Consortium.
Database (Oxford). 2012 Nov 17;2012:bas039.

FlyBase 102--advanced approaches to interrogating FlyBase.
St Pierre SE, Ponting L, Stefancsik R, McQuilton P; FlyBase Consortium.
Nucleic Acids Res. 2014 Jan;42(Database issue):D780-8.

tagtog: interactive and text-mining-assisted annotation of gene mentions in PLOS full-text articles.
Cejuela JM, McQuilton P, Ponting L, Marygold SJ, Stefancsik R, Millburn GH, Rost B; FlyBase Consortium.
Database (Oxford). 2014 Apr 7;2014(0):bau033.

FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations.
dos Santos G, Schroeder AJ, Goodman JL, Strelets VB, Crosby MA, Thurmond J, Emmert DB, Gelbart WM; FlyBase Consortium.
Nucleic Acids Res. 2015 Jan;43(Database issue):D690-7.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM; FlyBase Consortium.
G3 (Bethesda). 2015 Jun 24;5(8):1737-49.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM; FlyBase Consortium.
G3 (Bethesda). 2015 Jun 24;5(8):1721-36.

FlyBase: establishing a Gene Group resource for Drosophila melanogaster.
Attrill H, Falls K, Goodman JL, Millburn GH, Antonazzo G, Rey AJ, Marygold SJ; FlyBase Consortium.
Nucleic Acids Res. 2016 Jan 4;44(D1):D786-92.

FlyBase portals to human disease research using Drosophila models.
Millburn GH, Crosby MA, Gramates LS, Tweedie S; FlyBase Consortium.
Dis Model Mech. 2016 Mar;9(3):245-52.

Phenotypes Associated with Second Chromosome P Element Insertions in Drosophila melanogaster.
Kahsai L, Millburn GH, Cook KR.
G3 (Bethesda). 2016 Aug 9;6(8):2665-70.

Using FlyBase, a Database of Drosophila Genes and Genomes.
Marygold SJ, Crosby MA, Goodman JL; FlyBase Consortium.
Methods Mol Biol. 2016;1478:1-31.

FlyBase at 25: looking to the future.
Gramates LS, Marygold SJ, Santos GD, Urbano JM, Antonazzo G, Matthews BB, Rey AJ, Tabone CJ, Crosby MA, Emmert DB, Falls K, Goodman JL, Hu Y, Ponting L, Schroeder AJ, Strelets VB, Thurmond J, Zhou P; the FlyBase Consortium.
Nucleic Acids Res. 2017 Jan 4;45(D1):D663-D671.

Exploring FlyBase Data Using QuickSearch.
Marygold SJ, Antonazzo G, Attrill H, Costa M, Crosby MA, Dos Santos G, Goodman JL, Gramates LS, Matthews BB, Rey AJ, Thurmond J; FlyBase Consortium.
Curr Protoc Bioinformatics. 2016 Dec 8;56:1.31.1-1.31.23.

Types of DataProtein-Protein Interactions, Genetic Interaction Networks
Types of ToolsInteraction or functional association prediction
Genes / Proteins: 31,993
Interactions / Reactions: 69,742
Experiments / PubMed IDs: 218,669
Last Content Update: June 20th, 2017
Major OrganismsDrosophila melanogaster
Relative Popularity2120
Homepage Uptime StatisticsWebsite tracker - uptime monitoring service
Back to the List

"Pathguide: the pathway resource list" is maintained by Gary Bader1.
The website was originally created by Michael Cary 2 and was significantly updated and redesigned by Vuk Pavlovic1.
Thanks to Emek Demir for the Pathguide name.

1. Bader Lab
2. Sander Group

website tracker